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what's the matter with you? meaning in German

EnglishGerman
What's the matter with you? [UK: ˈwɒts ðə ˈmæ.tə(r) wɪð juː]
[US: ˈhwʌts ðə ˈmæ.tər wɪθ ˈjuː]

Was ist (mit) Ihnen?