Sistine(of or pertaining to Pope Sixtus) adjective [UK: ˈsɪ.ˈstiːn] [US: ˈsɪ.ˈstiːn]The Sistine Chapel is a vast chapel built inside the Vatican Palace in 1473. = La Capilla Sixtina es una extensa capilla construída dentro del Palacio Vaticano en el 1473.