regretfully(in a regretful manner) adverb [UK: rɪ.ˈɡret.fə.li] [US: rɪ.ˈɡret.fə.li]
regrettably(in a manner inspiring or deserving regret) adverb [UK: rɪ.ˈɡre.tə.bli] [US: rɪ.ˈɡre.tə.bli]Regrettably, we have not received your reply. = Lamentablemente, no hemos recibido tu respuesta.
unfortunately(happening through bad luck) adverb [UK: ʌn.ˈfɔː.tʃʊ.nət.li] [US: ʌn.ˈfɔːr.tʃə.nət.li]Unfortunately, she lives abroad. = Lamentablemente, ella vive en el extranjero.